SCHEMBL29633944

SCHEMBL29633944

Cc1cc(C)c(-c2ccccn2)c(C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.55
NPC1 O15118 5/20 0.55
CCR1 P32246 4/20 0.54
CCR5 P51681 4/20 0.54
CCR8 P51685 4/20 0.54
LMNA P02545 3/20 0.54
METAP1 P53582 3/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
TDP1 Q9NUW8 2/20 0.52
TP53 P04637 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
ALOX15 P16050 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
RAB9A P51151 3/20 0.46
HTT P42858 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3612264 1.00 KDM4E (0.55) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL28825785 0.88 KDM4E (0.49) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL19228163 0.87 KDM4E (0.47) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL17229164 0.86 CYP2A6 (0.46) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL14073530 0.84 GRM5 (0.48) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL12564832 0.84 CCR1 (0.56) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL12319817 0.83 KDM4E (0.52) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL4726132 0.82 KDM4E (0.59) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL30824691 0.82 KDM4E (0.59) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL18760760 0.82 KDM4E (0.50) KDM4ENPC1CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119451683-A Oligonucleotide compositions and methods thereof 艾米利克斯制药公司 2025-02-14 CN disclosed
CN-108135921-B Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2023-10-17 CN disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
CN-114761395-A GLP-1 receptor agonists 现代药品株式会社 2022-07-15 CN disclosed
CN-114533900-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2022-05-27 CN disclosed
CN-114206389-A Multivalent ligand clusters for targeted delivery of therapeutic agents 有丝分裂疗法有限责任公司 2022-03-18 CN disclosed