SCHEMBL3612264

SCHEMBL3612264

Cc1cc(C)c(-c2ccccn2)c(C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.55
NPC1 O15118 5/20 0.55
CCR1 P32246 4/20 0.54
CCR5 P51681 4/20 0.54
CCR8 P51685 4/20 0.54
LMNA P02545 3/20 0.54
METAP1 P53582 3/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
TDP1 Q9NUW8 2/20 0.52
TP53 P04637 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
ALOX15 P16050 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
RAB9A P51151 3/20 0.46
HTT P42858 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633944 1.00 KDM4E (0.55) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL28825785 0.88 KDM4E (0.49) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL19228163 0.87 KDM4E (0.47) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL17229164 0.86 CYP2A6 (0.46) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL14073530 0.84 GRM5 (0.48) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL12564832 0.84 CCR1 (0.56) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL12319817 0.83 KDM4E (0.52) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL4726132 0.82 KDM4E (0.59) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL30824691 0.82 KDM4E (0.59) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL18760760 0.82 KDM4E (0.50) KDM4ENPC1CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12104002-B2 Monobidentate aminopyridine group IV transition metal olefin copolymerization catalysts with ultra-high molecular weight capability and ultra-low comonomer incorporation DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-01 US disclosed
US-11814460-B2 Pyridyl hydroxyl amine catalyst compounds and systems for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-11-14 US disclosed
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
EP-3947481-B1 MONOBIDENTATE AMINOPYRIDINE GROUP IV TRANSITION METAL OLEFIN COPOLYMERIZATION CATALYSTS WITH ULTRA-HIGH MOLECULAR WEIGHT CAPABILITY AND ULTRA-LOW COMONOMER INCORPORATION DOW GLOBAL TECHNOLOGIES LLC (US) 2023-08-30 EP disclosed
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20220162354-A1 MONOBIDENTATE AMINOPYRIDINE GROUP IV TRANSITION METAL OLEFIN COPOLYMERIZATION CATALYSTS WITH ULTRA-HIGH MOLECULAR WEIGHT CAPABILITY AND ULTRA-LOW COMONOMER INCORPORATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-05-26 US disclosed
US-20220127387-A1 Pyridyl Hydroxyl Amine Catalyst Compounds and Systems for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-04-28 US disclosed
EP-3947481-A1 MONOBIDENTATE AMINOPYRIDINE GROUP IV TRANSITION METAL OLEFIN COPOLYMERIZATION CATALYSTS WITH ULTRA-HIGH MOLECULAR WEIGHT CAPABILITY AND ULTRA-LOW COMONOMER INCORPORATION Dow Global Technologies LLC (US) 2022-02-09 EP disclosed
US-11233203-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-01-25 US disclosed
WO-2020197907-A1 MONOBIDENTATE AMINOPYRIDINE GROUP IV TRANSITION METAL OLEFIN COPOLYMERIZATION CATALYSTS WITH ULTRA-HIGH MOLECULAR WEIGHT CAPABILITY AND ULTRA-LOW COMONOMER INCORPORATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-01 WO disclosed
CN-101835745-B Method for producing disulfonic acid compound, asymmetric mannich catalyst, method for producing beta-aminocarbonyl derivative, and disulfonate salt UNIV NAGOYA NAT UNIV CORP 2013-08-28 CN disclosed
US-8211820-B2 Catalyst composition, and process for production of cross-coupling compound using the same KYOTO UNIVERSITY (JP) 2012-07-03 US disclosed
CN-101835745-A Method for producing disulfonic acid compound, asymmetric mannich catalyst, method for producing beta-aminocarbonyl derivative, and novel disulfonate UNIV NAGOYA NAT UNIV CORP 2010-09-15 CN disclosed
US-20100094018-A1 CATALYST COMPOSITION, AND PROCESS FOR PRODUCTION OF CROSS-COUPLING COMPOUND USING THE SAME KYOTO UNIVERSITY (JP) 2010-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MGLL, SELENOI, APOL1 KDM4E 3250/4885NPC1 3111/4885CCR1 2772/4885
US-11814460-B2 Pyridyl hydroxyl amine catalyst compounds and systems for Olefin Polymerization MAOB, MAOA, AOC2 KDM4E 2718/4885NPC1 4200/4885CCR1 4675/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 KDM4E 2608/4885NPC1 3285/4885CCR1 3163/4885
US-11233203-B2 Organic electroluminescent materials and devices L1CAM, SOD1, EPCAM KDM4E 1841/4885NPC1 4023/4885CCR1 3867/4885
US-20100094018-A1 CATALYST COMPOSITION, AND PROCESS FOR PRODUCTION OF CROSS-COUPLING COMPOUND USING THE SAME F11, PYM1, CA2 KDM4E 2771/4885NPC1 1804/4885CCR1 2366/4885
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRM1, OPRD1, OXER1 KDM4E 3356/4885NPC1 2178/4885CCR1 730/4885
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, YBX3, LBR KDM4E 2057/4885NPC1 3523/4885CCR1 632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.