Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849652 | 1.00 | TSHR (0.53) | TSHRLMNAPTPRCALDH1A1CFTR | |
| SCHEMBL28684512 | 0.93 | PTGER1 (0.52) | TSHRLMNAPTPRCALDH1A1CFTR | |
| SCHEMBL13117430 | 0.91 | TSHR (0.59) | TSHRLMNAPTPRCALDH1A1CFTR | |
| SCHEMBL20763545 | 0.89 | TSHR (0.59) | TSHRPTPRCALDH1A1HSD17B10MEN1 | |
| SCHEMBL3511612 | 0.89 | LMNA (0.59) | TSHRLMNAPTPRCALDH1A1CFTR | |
| SCHEMBL13117416 | 0.88 | TSHR (0.51) | TSHRLMNAPTPRCALDH1A1CFTR | |
| SCHEMBL29918042 | 0.87 | PDCD1 (0.60) | TSHRLMNAALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL2898209 | 0.87 | MYC (0.54) | TSHRLMNAPTPRCALDH1A1CFTR | |
| SCHEMBL5533081 | 0.87 | PDCD1 (0.60) | TSHRLMNAALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL13117406 | 0.87 | LMNA (0.49) | TSHRLMNAPTPRCALDH1A1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787766-B2 | Compound having PD-L1 inhibitory activity, preparation method therefor and use thereof | SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) | 2023-10-17 | — | — | US | disclosed |
| CN-111386116-B | Compound with PD-L1 inhibitory activity, preparation method and application thereof | 上海轶诺药业有限公司 | 2022-06-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787766-B2 | Compound having PD-L1 inhibitory activity, preparation method therefor and use thereof | CD274, PDCD1, PDCD1LG2 | TSHR 3322/4885LMNA 1616/4885PTPRC 1429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.