SCHEMBL29634678

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	9/20	0.59

▸	MAGI3	Q5TCQ9	1/20	0.58

▸	BACE1	P56817	1/20	0.57

▸	RXFP1	Q9HBX9	1/20	0.56

▸	TLR2	O60603	3/20	0.55

▸	PTH1R	Q03431	2/20	0.55

▸	NPBWR1	P48145	2/20	0.55

▸	ECE1	P42892	1/20	0.54

▸	MUS81	Q96NY9	1/20	0.54

▸	KISS1R	Q969F8	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30874388	0.97	GLP1R (0.60)	GLP1RMAGI3BACE1RXFP1PTH1R
SCHEMBL31099263	0.94	GLP1R (0.63)	GLP1RRXFP1PTH1RNPBWR1ECE1
SCHEMBL29634675	0.94	GLP1R (0.63)	GLP1RRXFP1PTH1RNPBWR1ECE1
SCHEMBL16063027	0.94	GLP1R (0.55)	GLP1RBACE1RXFP1PTH1RNPBWR1
SCHEMBL30874405	0.92	RXFP1 (0.64)	GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL30874380	0.92	EDNRA (0.58)	MAGI3BACE1KISS1R
SCHEMBL30874398	0.91	GLP1R (0.62)	GLP1RMAGI3RXFP1PTH1RECE1
SCHEMBL30819419	0.91	GLP1R (0.62)	GLP1RRXFP1PTH1RNPBWR1ECE1
SCHEMBL31688342	0.90	GLP1R (0.63)	GLP1RNPBWR1ECE1MUS81KISS1R
SCHEMBL31093453	0.89	RXFP1 (0.69)	GLP1RRXFP1PTH1RECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110878127-B	Long-acting recombinant GLP1-Fc-CD47 protein and preparation and application thereof	浙江柏拉阿图医药科技有限公司	2022-06-28	—	—	CN	disclosed