Sugi Predict

Sugi Predict / Compounds / SCHEMBL31099263

SCHEMBL31099263

SCHEMBL31099263

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 13/20 0.63
▸ RXFP1 Q9HBX9 1/20 0.61
▸ PTH1R Q03431 3/20 0.59
▸ ECE1 P42892 1/20 0.59
▸ MUS81 Q96NY9 1/20 0.59
▸ NPBWR1 P48145 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29634675 1.00 GLP1R (0.63) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL30874388 0.95 GLP1R (0.60) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL29634678 0.94 GLP1R (0.59) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL30183270 0.94 RXFP1 (0.70) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL29462132 0.94 RXFP1 (0.70) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL31453813 0.93 RXFP1 (0.70) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL30635326 0.92 RXFP1 (0.70) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL30874405 0.91 RXFP1 (0.64) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL31093453 0.91 RXFP1 (0.69) GLP1RRXFP1PTH1RECE1MUS81
SCHEMBL16063027 0.91 GLP1R (0.55) GLP1RRXFP1PTH1RECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12115225-B2 GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof ASTRAZENECA AB (SE) 2024-10-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12115225-B2 GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof GLP1R, GIPR, GRPR GLP1R 1/4885RXFP1 35/4885PTH1R 184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.