SCHEMBL29634680

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	13/20	0.64

▸	BACE2	Q9Y5Z0	6/20	0.64

▸	OPRM1	P35372	4/20	0.60

▸	OPRD1	P41143	4/20	0.60

▸	OPRK1	P41145	1/20	0.60

▸	CTSD	P07339	1/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31538473	0.95	OPRM1 (0.61)	BACE1BACE2OPRM1OPRD1OPRK1
SCHEMBL30721600	0.91	TFPI (0.64)	BACE1BACE2
SCHEMBL31510101	0.91	BACE1 (0.67)	BACE1BACE2OPRM1OPRD1OPRK1
SCHEMBL29375389	0.91	BACE1 (0.56)	BACE1BACE2OPRM1OPRD1CTSD
SCHEMBL29375740	0.91	BACE1 (0.56)	BACE1BACE2OPRM1OPRD1CTSD
SCHEMBL30874383	0.91	BACE1 (0.63)	BACE1BACE2OPRM1OPRD1OPRK1
SCHEMBL30721553	0.90	TFPI (0.66)	BACE1BACE2
SCHEMBL1274597	0.90	OPRM1 (0.57)	BACE1BACE2OPRM1OPRD1OPRK1
SCHEMBL31688324	0.89	BACE1 (0.66)	BACE1BACE2OPRM1OPRD1OPRK1
SCHEMBL30467092	0.89	TFPI (0.62)	BACE1BACE2OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110878127-B	Long-acting recombinant GLP1-Fc-CD47 protein and preparation and application thereof	浙江柏拉阿图医药科技有限公司	2022-06-28	—	—	CN	disclosed