SCHEMBL29634744

SCHEMBL29634744

Clc1ccc2ccc(Cl)c3c4c(Cl)cc(Br)c5c(Br)cc(Cl)c(c1c23)c54

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
HSD17B10 Q99714 2/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
CYP1B1 Q16678 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
CSNK2A1 P68400 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23291424 1.00 CYP2A6 (0.31) CYP2A6ALDH1A1TSHRHSD17B10CYP1A1
SCHEMBL15517841 0.83 AHR (0.36) TSHR
SCHEMBL29962329 0.78 TSHR (0.39) CYP2A6ALDH1A1TSHRHSD17B10CYP1A1
SCHEMBL9512355 0.78 TSHR (0.39) CYP2A6ALDH1A1TSHRHSD17B10CYP1A1
SCHEMBL30702232 0.73 CYP2A6 (0.32) CYP2A6ALDH1A1
SCHEMBL29106961 0.73 CYP2A6 (0.32) CYP2A6ALDH1A1
SCHEMBL15521481 0.71 ALDH1A1 (0.32) ALDH1A1CYP3A4HPGDMEN1KMT2A
SCHEMBL15521412 0.71 ALDH1A1 (0.32) ALDH1A1
SCHEMBL15521502 0.68 ALDH1A1 (0.30) ALDH1A1
SCHEMBL15521010 0.65 TYMS (0.38) ALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333617-B Fluorescent dye for lipid drop labeling and synthetic method and application thereof 中国科学院大连化学物理研究所 2022-06-03 CN claimed