Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.54 |
| ▸ | CTSC | P53634 | 3/20 | 0.52 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 7/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634931 | 0.94 | CALCRL (0.53) | CALCRLCTSCRENNAALAD2BACE1 | |
| SCHEMBL29430213 | 0.94 | CALCRL (0.55) | CALCRLCTSCRENNAALAD2MAPK8 | |
| SCHEMBL31122250 | 0.93 | CALCRL (0.53) | CALCRLCTSCRENBACE1MAPK8 | |
| SCHEMBL30123252 | 0.93 | CTSC (0.59) | CALCRLCTSCRENBACE1 | |
| SCHEMBL29531750 | 0.91 | CTSC (0.56) | CALCRLCTSCRENNAALAD2 | |
| SCHEMBL10618815 | 0.90 | CTSC (0.56) | CALCRLCTSCRENBACE1 | |
| SCHEMBL10618805 | 0.90 | CTSC (0.56) | CALCRLCTSCRENBACE1 | |
| SCHEMBL30017540 | 0.88 | REN (0.51) | CTSCRENNAALAD2BACE1BACE2 | |
| SCHEMBL29506880 | 0.88 | CALCRL (0.52) | CALCRLCTSCRENBACE1MAPK8 | |
| SCHEMBL30974255 | 0.87 | REN (0.56) | CALCRLCTSCREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997104-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2022-05-18 | — | — | EP | disclosed |