Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 18/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19866866 | 1.00 | ACACB (0.41) | ACACBFGFR4PIK3CAMTOR | |
| SCHEMBL29596935 | 1.00 | ACACB (0.41) | ACACBFGFR4PIK3CAMTOR | |
| SCHEMBL19630300 | 1.00 | ACACB (0.41) | ACACBFGFR4PIK3CAMTOR | |
| SCHEMBL22023340 | 0.92 | PIK3CA (0.42) | ACACBPIK3CAMTOR | |
| SCHEMBL29597799 | 0.92 | PIK3CA (0.42) | ACACBPIK3CAMTOR | |
| SCHEMBL29597797 | 0.90 | EGLN2 (0.38) | ACACBFGFR4PIK3CAMTOR | |
| SCHEMBL19866914 | 0.90 | EGLN2 (0.38) | ACACBFGFR4PIK3CAMTOR | |
| SCHEMBL21056320 | 0.80 | JAK2 (0.42) | FGFR4 | |
| SCHEMBL21056321 | 0.80 | JAK2 (0.42) | FGFR4 | |
| SCHEMBL19866735 | 0.75 | AR (0.46) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563091-B | FGFR4 inhibitor and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-04-29 | — | — | CN | disclosed |