Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042736 | 1.00 | GAA (0.35) | GAAHDAC1HDAC6HDAC5KMT2A | |
| SCHEMBL29635375 | 0.86 | KMT2A (0.33) | KMT2APPP1CA | |
| SCHEMBL22042753 | 0.86 | KMT2A (0.33) | KMT2APPP1CA | |
| SCHEMBL29635360 | 0.84 | CYP1A1 (0.31) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30151227 | 0.84 | GAA (0.54) | GAAKMT2APPP1CACYP1A2CYP2C9 | |
| SCHEMBL22042773 | 0.84 | GAA (0.54) | GAAKMT2APPP1CACYP1A2CYP2C9 | |
| SCHEMBL22042752 | 0.84 | CYP1A1 (0.31) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22042755 | 0.83 | ULK1 (0.33) | KMT2APPP1CAULK1 | |
| SCHEMBL29635357 | 0.83 | ULK1 (0.33) | KMT2APPP1CAULK1 | |
| SCHEMBL22042757 | 0.83 | HDAC1 (0.36) | GAAHDAC1HDAC6HDAC5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739689-B | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2022-06-03 | — | — | CN | disclosed |