Dibenzofuran

Dibenzofuran

SCHEMBL29635704

c1ccc2c(c1)oc1ccccc12

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.68
MAOA P21397 5/20 0.68
KDM4E B2RXH2 4/20 0.68
ALDH1A1 P00352 4/20 0.68
HPGD P15428 3/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
GLA P06280 1/20 0.68
CYP3A4 P08684 1/20 0.68
PGAM1 P18669 1/20 0.68
CASP1 P29466 1/20 0.68
CASP7 P55210 1/20 0.68
HSD17B10 Q99714 1/20 0.68
AHR P35869 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 1/20 0.61
NQO1 P15559 1/20 0.48
GAA P10253 1/20 0.48
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzofuran SCHEMBL8207 1.00 MAPT (0.68) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL9868133 1.00 MAPT (0.68) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL11775205 0.97 MAPT (0.65) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL21436811 0.97 MAPT (0.65) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL9932651 0.97 KDM4E (0.65) MAPTMAOAKDM4EALDH1A1HPGD
SCHEMBL24307195 0.97 MAPT (0.65) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL7262648 0.97 MAPT (0.65) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL7262652 0.97 MAPT (0.65) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL11564675 0.97 MAPT (0.65) MAPTMAOAKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL7592452 0.97 MAPT (0.65) MAPTMAOAKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118251034-A Organic light emitting diode and organic light emitting device 乐金显示有限公司 2024-06-25 CN claimed
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2025-06-24 US disclosed
CN-119872008-A Battery thermal management member 亚斯朋空气凝胶公司 2025-04-25 CN disclosed
WO-2025083006-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2025-04-24 WO disclosed
CN-119567649-A Thermal control member 亚斯朋空气凝胶公司 2025-03-07 CN disclosed
CN-115279583-B Battery thermal management member 亚斯朋空气凝胶公司 2025-01-14 CN disclosed
CN-115038580-B Thermal control member, and battery module and battery pack including the same 亚斯朋空气凝胶公司 2024-12-03 CN disclosed
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2023-01-10 US disclosed
US-11279687-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2022-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279687-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNT, NQO1 MAPT 694/4885MAOA 101/4885KDM4E 813/4885
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NNT MAPT 256/4885MAOA 115/4885KDM4E 1401/4885
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NQO1 MAPT 268/4885MAOA 115/4885KDM4E 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.