Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 15/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25962627 | 1.00 | KDM4E (0.61) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL2557276 | 0.88 | KDM4E (0.55) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL2557277 | 0.88 | KDM4E (0.55) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16798067 | 0.84 | KDM4E (0.63) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL6951249 | 0.81 | MEN1 (0.50) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9131609 | 0.80 | ERN1 (0.59) | ERN1 | |
| SCHEMBL10477862 | 0.80 | MEN1 (0.44) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL27493423 | 0.79 | PTPN1 (0.48) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL10881818 | 0.77 | GPR35 (0.59) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7359628 | 0.77 | PDE4A (0.47) | MEN1ALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161646-A2 | COMPOSITIONS AND METHODS FOR TREATING VIRUS INFECTION | Chan Zuckerberg Biohub, Inc. (US) | 2023-04-12 | — | — | EP | claimed |
| EP-4161646-A2 | COMPOSITIONS AND METHODS FOR TREATING VIRUS INFECTION | Chan Zuckerberg Biohub, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-114404396-B | Application of compound in preparation of antithrombotic drug | 广西医科大学第一附属医院 | 2023-03-07 | — | — | CN | disclosed |
| CN-114404396-B | Application of compound in preparation of antithrombotic drug | 广西医科大学第一附属医院 | 2023-03-07 | — | — | CN | disclosed |
| CN-114404396-A | Application of compound in preparation of antithrombotic drug | 广西医科大学第一附属医院 | 2022-04-29 | — | — | CN | disclosed |
| CN-114404396-A | Application of compound in preparation of antithrombotic drug | 广西医科大学第一附属医院 | 2022-04-29 | — | — | CN | disclosed |