Phelligridin D

Phelligridin D

SCHEMBL29635990

O=c1oc2cc(/C=C/c3ccc(O)c(O)c3)oc(=O)c2c2cc(O)c(O)cc12

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 2/20 0.86
PTPN1 P18031 1/20 0.76
KDM4E B2RXH2 3/20 0.55
MAPT P10636 3/20 0.55
ALOX12 P18054 3/20 0.55
HIF1A Q16665 3/20 0.55
MAPK1 P28482 2/20 0.55
ALDH1A1 P00352 2/20 0.55
LMNA P02545 2/20 0.55
POLB P06746 2/20 0.55
HPGD P15428 2/20 0.55
BLM P54132 2/20 0.55
PMP22 Q01453 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
CYP3A4 P08684 2/20 0.55
CYP2C9 P11712 2/20 0.55
ALOX15 P16050 2/20 0.55
THPO P40225 2/20 0.55
HSD17B10 Q99714 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phelligridin D SCHEMBL17394787 1.00 NT5E (0.86) NT5EPTPN1KDM4EMAPTALOX12
Phellibaumin A SCHEMBL29635999 0.90 NT5E (1.00) NT5EPTPN1KDM4EMAPTALOX12
Phelligridin C SCHEMBL29992860 0.90 NT5E (0.71) NT5EPTPN1KDM4EMAPTALOX12
Phelligridin I SCHEMBL31399402 0.87 PTPN1 (1.00) NT5EPTPN1KDM4EMAPTALOX12
Phelligridin H SCHEMBL29992913 0.87 NT5E (0.68) NT5EPTPN1KDM4EMAPTALOX12
Phellibaumin C SCHEMBL29637040 0.84 NT5E (0.64) NT5EPTPN1KDM4EMAPTALOX12
SCHEMBL20254520 0.76 KDM4E (0.65) NT5EPTPN1KDM4EMAPTALOX12
SCHEMBL20254622 0.76 KDM4E (0.65) NT5EPTPN1KDM4EMAPTALOX12
SCHEMBL29781217 0.76 KDM4E (0.65) NT5EPTPN1KDM4EMAPTALOX12
SCHEMBL8676491 0.72 KDM4E (0.60) NT5EPTPN1KDM4EMAPTALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119296634-A Construction method for analyzing pulmonary fibrosis target caused by inflammation of mulberry Huang Yaoxiao components 辽宁省农业科学院 2025-01-10 CN disclosed
CN-114573539-B Method for preparing compound Phellibaumin D from phellinus linteus medicinal material 中国科学院大连化学物理研究所 2024-11-05 CN disclosed
CN-116298043-A Screening method of inonotus obliquus active action quality markers and construction and application of chemical characterization map thereof 哈尔滨商业大学 2023-06-23 CN disclosed
CN-113577058-B Application of pyrone compound in preparation of lung cancer chemotherapy sensitization drug and drug 丽水市中心医院 2023-03-14 CN disclosed
CN-114403315-A Preparation method and preparation device of composite beverage based on Xiazine white mulberry phellinus igniarius and frosted mulberry leaves 夏津素源生物科技有限公司 2022-04-29 CN disclosed