Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29781217 | 0.83 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| SCHEMBL20254622 | 0.83 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| SCHEMBL20254520 | 0.83 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| SCHEMBL8675671 | 0.78 | HIF1A (0.48) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| Hispidin SCHEMBL28261094 | 0.75 | ALOX12 (1.00) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| Hispidin SCHEMBL3791520 | 0.75 | ALOX12 (1.00) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| Hispidin SCHEMBL246649 | 0.75 | ALOX12 (1.00) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| SCHEMBL8859595 | 0.75 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| Phelligridin B SCHEMBL31399401 | 0.74 | PTPN1 (0.57) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A | |
| SCHEMBL8859503 | 0.74 | MAPK1 (0.50) | KDM4EHSD17B10ALDH1A1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390673-A | 2-Pyrone compound and preparation method and application thereof | 青岛农业大学 | 2025-02-07 | — | — | CN | claimed |
| CN-119390673-A | 2-Pyrone compound and preparation method and application thereof | 青岛农业大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-119390673-A | 2-Pyrone compound and preparation method and application thereof | 青岛农业大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-114403315-A | Preparation method and preparation device of composite beverage based on Xiazine white mulberry phellinus igniarius and frosted mulberry leaves | 夏津素源生物科技有限公司 | 2022-04-29 | — | — | CN | disclosed |
| US-5731344-A | DIABETES, ATHEROSCLEROSIS, ARTERIOSCLEROSIS; INHIBITORS OF ADVANCED GLYCOSYLATION ENDPRODUCTS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-03-24 | — | — | US | disclosed |