Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 19/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30176757 | 0.89 | GRIN1 (0.56) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL30176775 | 0.79 | GRIN2B (0.54) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL29636060 | 0.79 | GRIN1 (0.54) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL29636022 | 0.73 | LMNA (0.58) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL20130009 | 0.71 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL11158720 | 0.71 | LMNA (0.59) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL30532161 | 0.70 | GRIN1 (0.54) | GRIN2BGRIN1 | |
| SCHEMBL20130013 | 0.69 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL11160869 | 0.68 | LMNA (0.59) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL2272829 | 0.68 | LMNA (0.69) | MEN1LMNAPABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989164-A | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-110062761-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-05-13 | — | — | CN | disclosed |