Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.37 |
| ▸ | CALCR | P30988 | 6/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636377 | 0.98 | KDM1A (0.42) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29886731 | 0.90 | MAPK8 (0.41) | MAPK8MAPK9MAPK10KDM1ACALCRL | |
| SCHEMBL29496505 | 0.90 | PRCP (0.42) | MAPK8MAPK9MAPK10 | |
| SCHEMBL29568411 | 0.88 | KDM1A (0.53) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL30973948 | 0.88 | MEN1 (0.42) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL30416888 | 0.87 | MAPK8 (0.42) | MAPK8MAPK9MAPK10CALCRL | |
| SCHEMBL30844370 | 0.87 | KDM1A (0.48) | MAPK8MAPK9MAPK10KDM1ACALCRL | |
| SCHEMBL30844273 | 0.87 | KDM1A (0.48) | MAPK8MAPK9MAPK10KDM1ACALCRL | |
| SCHEMBL29663559 | 0.86 | MAPK8 (0.46) | MAPK8MAPK9MAPK10 | |
| SCHEMBL31720924 | 0.86 | PRCP (0.41) | MAPK8MAPK9MAPK10KDM1ACALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187508-B1 | LYSOSOMAL TARGETING PEPTIDES AND USES THEREOF | BIOMARIN PHARM INC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20230241187-A1 | Lysosomal Targeting Peptides and Uses Thereof | BIOMARIN PHARMACEUTICAL INC. | 2023-08-03 | — | — | US | disclosed |
| US-20220354934-A1 | Lysosomal Targeting Peptides and Uses Thereof | BIOMARIN PHARMACEUTICAL INC. | 2022-11-10 | — | — | US | disclosed |
| US-11351231-B2 | Lysosomal targeting peptides and uses thereof | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-06-07 | — | — | US | disclosed |