SCHEMBL29496505

SCHEMBL29496505

C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ MAPK8 P45983 1/20 0.42
▸ MAPK9 P45984 1/20 0.42
▸ MAPK10 P53779 1/20 0.42
▸ DPP7 Q9UHL4 1/20 0.41
▸ NRP1 O14786 2/20 0.41
▸ F2 P00734 5/20 0.39
▸ MASP2 O00187 3/20 0.39
▸ NPY5R Q15761 3/20 0.36
▸ NPY1R P25929 2/20 0.36
▸ NPY4R P50391 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30416888 0.93 MAPK8 (0.42) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL29663559 0.93 MAPK8 (0.46) PRCPMAPK8MAPK9MAPK10NPY5R
SCHEMBL30193454 0.92 PRCP (0.44) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL29687469 0.92 MAPK8 (0.48) MEN1KMT2AMAPK8MAPK9MAPK10
SCHEMBL29824904 0.91 MEN1 (0.41) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL29496543 0.91 MEN1 (0.44) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL17711236 0.90 MEN1 (0.47) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL31487414 0.90 MEN1 (0.47) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL8759336 0.90 MEN1 (0.47) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL8759341 0.90 MEN1 (0.47) PRCPMEN1KMT2AMAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4388311-B1 METHODS COMPRISING THERAPEUTIC COMPOUNDS AND IN VITRO MAMMALIAN SKIN AMGEN INC (US) 2025-10-15 — — EP claimed
CN-112159461-B Synthesis method of cetrorelix 开封明仁药业有限公司 2023-03-10 — — CN disclosed
EP-3969467-A2 VARIANT SINGLE-CHAIN INSULIN ANALOGUES CASE WESTERN RESERVE UNIVERSITY (US) 2022-03-23 — — EP disclosed
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