Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022239 | 1.00 | STING1 (0.61) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20563177 | 0.94 | STING1 (0.61) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20022241 | 0.89 | STING1 (0.66) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL1590372 | 0.87 | STING1 (0.61) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20022240 | 0.85 | STING1 (0.61) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20338887 | 0.85 | PTPN2 (0.53) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20022261 | 0.83 | STING1 (0.66) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL29636423 | 0.83 | STING1 (0.66) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21452706 | 0.82 | STING1 (0.80) | STING1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL16396262 | 0.82 | PTPN2 (0.55) | STING1HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036001-B | Benzo [ b ] thiophene compounds as STING agonists | 默沙东公司 | 2022-03-22 | — | — | CN | disclosed |