Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670598 | 1.00 | NPSR1 (0.68) | NPSR1KMT2AMEN1TAAR1TSHR | |
| Phosphonic Acid SCHEMBL28146347 | 0.93 | NPSR1 (0.59) | NPSR1KMT2AMEN1TAAR1TSHR | |
| SCHEMBL1006607 | 0.89 | TSHR (0.58) | NPSR1KMT2AMEN1TAAR1TSHR | |
| SCHEMBL6207760 | 0.87 | TSHR (0.57) | NPSR1KMT2AMEN1TAAR1TSHR | |
| SCHEMBL13652507 | 0.86 | NPSR1 (0.59) | NPSR1KMT2AMEN1TSHRFFAR1 | |
| SCHEMBL10110930 | 0.86 | F13A1 (0.56) | NPSR1KMT2AMEN1TAAR1TSHR | |
| SCHEMBL14023721 | 0.85 | NPSR1 (0.57) | NPSR1KMT2AMEN1TSHRFFAR1 | |
| SCHEMBL31689801 | 0.85 | NPSR1 (0.68) | NPSR1KMT2AMEN1TSHRFFAR1 | |
| SCHEMBL69559 | 0.85 | NPSR1 (0.57) | NPSR1KMT2AMEN1TSHRFFAR1 | |
| SCHEMBL324789 | 0.85 | NPSR1 (0.68) | NPSR1KMT2AMEN1TSHRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013287-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118613490-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118076623-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117940445-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-110305010-B | Preparation method of 2, 5-dimethylphenylacetic acid | 江苏中旗科技股份有限公司 | 2022-05-13 | — | — | CN | disclosed |