Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 11/20 | 0.53 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636742 | 0.90 | ACP1 (0.50) | ACP1SMARCA2SLC2A1 | |
| SCHEMBL23015126 | 0.90 | ACP1 (0.50) | ACP1SMARCA2SLC2A1 | |
| SCHEMBL16098534 | 0.84 | SLC2A1 (0.65) | ACP1SMARCA2KDM4ESLC2A1 | |
| SCHEMBL6749969 | 0.84 | SLC2A1 (0.70) | ACP1SMARCA2ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL16102182 | 0.83 | SLC2A1 (0.67) | ACP1SMARCA2KDM4ESLC2A1 | |
| Hydrochloric Acid SCHEMBL16097746 | 0.83 | SLC2A1 (0.67) | ACP1SMARCA2KDM4ESLC2A1 | |
| SCHEMBL6751610 | 0.82 | SLC2A1 (0.61) | ACP1SMARCA2KDM4ENPC1MAPT | |
| SCHEMBL6748821 | 0.82 | SLC2A1 (0.60) | ACP1SMARCA2KDM4ENPC1MAPT | |
| SCHEMBL15521729 | 0.81 | ADRA2A (0.75) | ACP1ADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL29636750 | 0.81 | ACP1 (0.48) | ACP1SMARCA2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017492-A1 | MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED DISORDERS | Biohaven Therapeutics Ltd. (US) | 2022-06-29 | — | — | EP | claimed |
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |