Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745519 | 0.86 | ACMSD (0.49) | SOS1LDHAACMSDMCL1TSHR | |
| SCHEMBL8851047 | 0.84 | MCL1 (0.57) | SOS1LDHAPTPN1GFERALDH1A1 | |
| SCHEMBL28379363 | 0.82 | SOS1 (0.56) | SOS1PTPN1ALDH1A1KDM4EGAA | |
| SCHEMBL6935260 | 0.82 | CA12 (0.53) | SOS1LDHAPTPN1GFERALDH1A1 | |
| SCHEMBL28625653 | 0.80 | POLB (0.47) | SOS1ALDH1A1KDM4EGAAACMSD | |
| SCHEMBL6937705 | 0.78 | CA12 (0.53) | LDHAGFERALDH1A1KDM4EGAA | |
| SCHEMBL16755708 | 0.78 | SOS1 (0.55) | SOS1PTPN1GFERACMSDMCL1 | |
| SCHEMBL11795658 | 0.77 | ESR2 (0.46) | ALDH1A1KDM4EGAACYP1A2MEN1 | |
| SCHEMBL1754468 | 0.76 | ESR2 (0.47) | ALDH1A1KDM4EGAACYP1A2MEN1 | |
| SCHEMBL745266 | 0.75 | GRIN2D (0.44) | PTPN1ALDH1A1KDM4EGAAACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |