Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 6/20 | 0.40 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23015287 | 1.00 | ACACB (0.41) | ACACBPDE10AACP1ACACASLC2A1 | |
| SCHEMBL29636803 | 0.92 | ACP1 (0.42) | ACACBACP1ACACA | |
| SCHEMBL29636838 | 0.82 | SMYD3 (0.39) | ACACBACACA | |
| SCHEMBL23015253 | 0.82 | SMYD3 (0.39) | ACACBACACA | |
| SCHEMBL26967672 | 0.77 | SLC34A1 (0.41) | SLC2A1BRD4 | |
| SCHEMBL29636780 | 0.76 | ACP1 (0.58) | ACP1 | |
| SCHEMBL23015387 | 0.76 | ACP1 (0.58) | ACP1 | |
| SCHEMBL23015131 | 0.73 | SLC2A1 (0.51) | PDE10AACP1SLC2A1 | |
| SCHEMBL29636834 | 0.73 | SLC2A1 (0.51) | PDE10AACP1SLC2A1 | |
| SCHEMBL26967676 | 0.73 | BRD4 (0.41) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017492-A1 | MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED DISORDERS | Biohaven Therapeutics Ltd. (US) | 2022-06-29 | — | — | EP | disclosed |