Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 5/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1825492 | 1.00 | PRMT1 (0.48) | PRMT1APPMAPTMEN1KMT2A | |
| Iodide SCHEMBL29406768 | 1.00 | PRMT1 (0.48) | PRMT1APPMAPTMEN1KMT2A | |
| Iodide SCHEMBL1615556 | 1.00 | PRMT1 (0.48) | PRMT1APPMAPTMEN1KMT2A | |
| Iodide SCHEMBL29552429 | 1.00 | PRMT1 (0.48) | PRMT1APPMAPTMEN1KMT2A | |
| SCHEMBL343730 | 0.99 | PRMT1 (0.49) | PRMT1APPMAPTMEN1KMT2A | |
| SCHEMBL12355233 | 0.99 | PRMT1 (0.49) | PRMT1APPMAPTMEN1KMT2A | |
| SCHEMBL15026324 | 0.99 | PRMT1 (0.49) | PRMT1APPMAPTMEN1KMT2A | |
| SCHEMBL435197 | 0.99 | PRMT1 (0.49) | PRMT1APPMAPTMEN1KMT2A | |
| SCHEMBL1925058 | 0.99 | PRMT1 (0.49) | PRMT1APPMAPTMEN1KMT2A | |
| Perchlorate SCHEMBL3806537 | 0.96 | MAPT (0.51) | PRMT1APPMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024155728-A1 | NANOPARTICLES AND METHODS OF USE | QANA THERAPEUTICS INC. (US) | 2024-07-25 | — | — | WO | claimed |
| WO-2025080206-A1 | METHOD AND DEVICE FOR DRUG DELIVERY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2025-04-17 | — | — | WO | disclosed |
| EP-4450045-A1 | ULTRASONICALLY-ENHANCED CONTINUOUS AND LARGE-SCALE PRODUCTION METHOD FOR NANO-FORMULATIONS | Shanghai Best-Link Bioscience, LLC (CN) | 2024-10-23 | — | — | EP | disclosed |
| WO-2024155728-A1 | NANOPARTICLES AND METHODS OF USE | QANA THERAPEUTICS INC. (US) | 2024-07-25 | — | — | WO | disclosed |
| EP-4224536-A2 | TRANSPARENT ENERGY-HARVESTING DEVICES | Board Of Trustees Of Michigan State University (US) | 2023-08-09 | — | — | EP | disclosed |
| US-20230112218-A1 | THREE-COMPONENT PHOTO INITIATING SYSTEMS FOR THE RED AND NEAR INFRARED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-04-13 | — | — | US | disclosed |
| CN-114748639-A | Photosensitizer-hydroxyalkyl starch-polypeptide coupled amphiphilic macromolecular compound, nano drug delivery system and preparation method thereof | 华中科技大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114470231-A | Nano drug delivery system of folic acid-hydroxyalkyl starch macromolecule stable co-carried photosensitizer and small molecule prodrug, preparation and application thereof | 华中科技大学 | 2022-05-13 | — | — | CN | disclosed |