Sugi Predict

Sugi Predict / Compounds / SCHEMBL435197

SCHEMBL435197

SCHEMBL435197

CCCN1/C(=C/C=C2\CCCC(/C=C/C3=[N+](CCC)c4ccccc4C3(C)C)=C2Cl)C(C)(C)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 5/20 0.49
▸ APP P05067 2/20 0.48
▸ MAPT P10636 4/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ NPSR1 Q6W5P4 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ USP2 O75604 1/20 0.46
▸ S1PR2 O95136 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ ALPG P10696 1/20 0.46
▸ THRB P10828 1/20 0.46
▸ PKM P14618 1/20 0.46
▸ XBP1 P17861 1/20 0.46
▸ CRHBP P24387 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1925058 1.00 PRMT1 (0.49) PRMT1APPMAPTMEN1KMT2A
SCHEMBL12355233 1.00 PRMT1 (0.49) PRMT1APPMAPTMEN1KMT2A
SCHEMBL343730 1.00 PRMT1 (0.49) PRMT1APPMAPTMEN1KMT2A
SCHEMBL15026324 1.00 PRMT1 (0.49) PRMT1APPMAPTMEN1KMT2A
Iodide SCHEMBL1615556 0.99 PRMT1 (0.48) PRMT1APPMAPTMEN1KMT2A
Iodide SCHEMBL1825492 0.99 PRMT1 (0.48) PRMT1APPMAPTMEN1KMT2A
Iodide SCHEMBL29637270 0.99 PRMT1 (0.48) PRMT1APPMAPTMEN1KMT2A
Iodide SCHEMBL29406768 0.99 PRMT1 (0.48) PRMT1APPMAPTMEN1KMT2A
Iodide SCHEMBL29552429 0.99 PRMT1 (0.48) PRMT1APPMAPTMEN1KMT2A
Perchlorate SCHEMBL3806537 0.97 MAPT (0.51) PRMT1APPMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374253-A1 USE OF RED TO NEAR-INFRARED HEAT-GENERATING ORGANIC DYES FOR REPROCESSING/RECYCLING POLYMERS UNIVERSITÉ D'AIX-MARSEILLE (FR) 2023-11-23 — — US disclosed
US-20230374253-A1 USE OF RED TO NEAR-INFRARED HEAT-GENERATING ORGANIC DYES FOR REPROCESSING/RECYCLING POLYMERS UNIVERSITÉ D'AIX-MARSEILLE (FR) 2023-11-23 — — US disclosed
US-20230248832-A1 Small Molecule Ligand-Drug Conjugates for Targeted Cancer Therapy UNIV EMORY (US) 2023-08-10 — — US disclosed
US-20230248832-A1 Small Molecule Ligand-Drug Conjugates for Targeted Cancer Therapy UNIV EMORY (US) 2023-08-10 — — US disclosed
US-20230203239-A1 Cyclic ether-anhydride photopolyaddition and uses thereof UNIVERSITÉ DE HAUTE-ALSACE (FR) 2023-06-29 — — US disclosed
US-20230203239-A1 Cyclic ether-anhydride photopolyaddition and uses thereof UNIVERSITÉ DE HAUTE-ALSACE (FR) 2023-06-29 — — US disclosed
WO-2022156424-A1 AMPHIPHILIC MOLECULAR SELF-ASSEMBLY NANODRUG FOR TUMOR TREATMENT, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国科学院深圳先进技术研究院 2022-07-28 — — WO disclosed
US-20180200389-A1 PHOTOACOUSTIC VOLTAGE-SENSITIVE DYES FOR IN VIVO IMAGING THE JOHNS HOPKINS UNIVERSITY 2018-07-19 — — US disclosed
US-20180179233-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2018-06-28 — — US disclosed
US-20180127830-A1 FLUORESCENT PROBES FOR ABASIC SITE DETECTION CASE WESTERN RESERVE UNIVERSITY 2018-05-10 — — US disclosed
US-20130157463-A1 NEAR-INFRARED ABSORBING FILM COMPOSITION FOR LITHOGRAPHIC APPLICATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-06-20 — — US disclosed
US-20130101517-A1 DEVELOPMENT OF PHOTOSTABLE NEAR-IR CYANINE DYES FOR IN VIVO IMAGING AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-04-25 — — US disclosed
US-20120065384-A1 FLUORESCENT MRI PROBE THE UNIVERSITY OF TOKYO (JP) 2012-03-15 — — US disclosed
WO-2011119114-A1 DEVELOPMENT OF PHOTOSTABLE NEAR-IR CYANINE DYES FOR IN VIVO IMAGING NATIONAL UNIVERSITY OF SINGAPORE (SG) 2011-09-29 — — WO disclosed
US-20110190480-A1 CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES IGNATYEV NIKOLAI MYKOLA 2011-08-04 — — US disclosed
US-20110190480-A1 CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES IGNATYEV NIKOLAI MYKOLA 2011-08-04 — — US disclosed
US-20110085974-A1 SMALL MOLECULE LIGAND-DRUG CONJUGATES FOR TARGETED CANCER THERAPY CEDARS-SINAI MEDICAL CENTER (US) 2011-04-14 — — US disclosed
WO-2011031396-A2 NEAR-INFRARED ABSORBING FILM COMPOSITIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-03-17 — — WO disclosed
US-20110042771-A1 Near-Infrared Absorbing Film Compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-02-24 — — US disclosed
US-20070298507-A1 Fluorescent Probe Nagano, Tetsuo (JP) 2007-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190480-A1 CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES ZAP70, MYLK3, KIT PRMT1 2119/4885APP 3880/4885MAPT 3351/4885
US-20230248832-A1 Small Molecule Ligand-Drug Conjugates for Targeted Cancer Therapy SELL, EPCAM, SELPLG PRMT1 2454/4885APP 4881/4885MAPT 3720/4885
US-20120065384-A1 FLUORESCENT MRI PROBE GLRA1, GLRA3, GDI1 PRMT1 491/4885APP 4581/4885MAPT 3584/4885
US-20070298507-A1 Fluorescent Probe PYM1, NOX3, NCF1 PRMT1 68/4885APP 4405/4885MAPT 4139/4885
US-20180127830-A1 FLUORESCENT PROBES FOR ABASIC SITE DETECTION OGG1, UNG, AP2B1 PRMT1 2315/4885APP 4764/4885MAPT 4782/4885
US-20180200389-A1 PHOTOACOUSTIC VOLTAGE-SENSITIVE DYES FOR IN VIVO IMAGING KCNN2, KCNN1, KCNN3 PRMT1 4635/4885APP 1453/4885MAPT 1828/4885
US-20180179233-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 PRMT1 1988/4885APP 3950/4885MAPT 1631/4885
US-20110085974-A1 SMALL MOLECULE LIGAND-DRUG CONJUGATES FOR TARGETED CANCER THERAPY SELL, EPCAM, SELPLG PRMT1 2454/4885APP 4881/4885MAPT 3720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.