Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.79 |
| ▸ | SLC16A3 | O15427 | 10/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21565735 | 1.00 | KCNH2 (0.79) | KCNH2SLC16A3MEN1KMT2AMCHR1 | |
| SCHEMBL23116279 | 1.00 | KCNH2 (0.79) | KCNH2SLC16A3MEN1KMT2AMCHR1 | |
| SCHEMBL21565528 | 0.88 | KCNH2 (1.00) | KCNH2SLC16A3MEN1KMT2AHRH3 | |
| SCHEMBL23116299 | 0.88 | KCNH2 (1.00) | KCNH2SLC16A3MEN1KMT2AHRH3 | |
| SCHEMBL21551376 | 0.86 | SLC16A3 (1.00) | KCNH2SLC16A3MEN1KMT2AMCHR1 | |
| SCHEMBL21565589 | 0.86 | SLC16A3 (1.00) | KCNH2SLC16A3MEN1KMT2AMCHR1 | |
| SCHEMBL21551378 | 0.86 | SLC16A3 (1.00) | KCNH2SLC16A3MEN1KMT2AMCHR1 | |
| SCHEMBL23116333 | 0.86 | SLC16A3 (0.81) | KCNH2SLC16A3MEN1KMT2ADYRK1A | |
| SCHEMBL23116284 | 0.86 | KCNH2 (0.81) | KCNH2SLC16A3MEN1KMT2AHRH3 | |
| SCHEMBL21565663 | 0.86 | KCNH2 (0.81) | KCNH2SLC16A3MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790879-B1 | TRIAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE IN TREATING CANCER | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |