SCHEMBL29637604

SCHEMBL29637604

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 19/20 0.54
▸ UTS2R Q9UKP6 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30919237 0.95 KISS1R (0.54) KISS1R
SCHEMBL29636525 0.94 KISS1R (0.53) KISS1R
SCHEMBL34468395 0.94 KISS1R (0.53) KISS1R
SCHEMBL29476642 0.93 KISS1R (0.53) KISS1R
SCHEMBL31406265 0.93 ERAP2 (0.54) KISS1R
SCHEMBL30903464 0.91 KISS1R (0.56) KISS1R
SCHEMBL30529926 0.91 KISS1R (0.58) KISS1R
SCHEMBL30529927 0.91 KISS1R (0.58) KISS1R
SCHEMBL31607064 0.91 ERAP2 (0.52) KISS1R
SCHEMBL29672123 0.91 KISS1R (0.55) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459894-B2 Orally active melanocortin receptor-4 compounds PALATIN TECHNOLOGIES, INC. (US) 2025-11-04 — — US disclosed
US-20220204450-A1 Orally Active Melanocortin Receptor-4 Compounds PALATIN TECHNOLOGIES, INC. (US) 2022-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12459894-B2 Orally active melanocortin receptor-4 compounds MC4R, MC1R, MC3R KISS1R 118/4885UTS2R 128/4885
US-20220204450-A1 Orally Active Melanocortin Receptor-4 Compounds MC4R, MC1R, MC3R KISS1R 118/4885UTS2R 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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