Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622817 | 1.00 | FAAH (0.72) | FAAHGAASOAT1MEN1TP53 | |
| SCHEMBL29637719 | 1.00 | FAAH (0.72) | FAAHGAASOAT1MEN1TP53 | |
| SCHEMBL6683810 | 1.00 | FAAH (0.72) | FAAHGAASOAT1MEN1TP53 | |
| SCHEMBL4758347 | 0.98 | FAAH (0.68) | FAAHGAASOAT1MEN1TP53 | |
| Octadecanoic Acid Amide SCHEMBL29144433 | 0.94 | FAAH (0.84) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Palmitamide SCHEMBL28248066 | 0.94 | FAAH (0.84) | FAAHSOAT1MEN1TP53CYP1A2 | |
| SCHEMBL6679258 | 0.93 | FAAH (0.61) | FAAHGAASOAT1MEN1TP53 | |
| SCHEMBL14500856 | 0.92 | FAAH (0.62) | FAAHMEN1KMT2AEPHX2DNM1 | |
| Propionic Acid SCHEMBL28737137 | 0.92 | FAAH (0.62) | FAAHGAAMEN1KMT2AEPHX2 | |
| Propionic Acid SCHEMBL28737145 | 0.92 | FAAH (0.62) | FAAHGAAMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089408-A1 | TETRAHYDRONAPHTHALENE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |