Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.51 |
| ▸ | JAK3 | P52333 | 9/20 | 0.48 |
| ▸ | LCK | P06239 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017664 | 1.00 | BTK (0.51) | BTKJAK3LCKPPARDPPARA | |
| SCHEMBL29637912 | 0.90 | BTK (0.53) | BTKJAK3LCKEGFR | |
| SCHEMBL29017728 | 0.90 | BTK (0.53) | BTKJAK3LCKEGFR | |
| SCHEMBL29017709 | 0.90 | KMT2A (0.44) | BTKJAK3PPARDPPARA | |
| SCHEMBL29017653 | 0.90 | CNR1 (0.44) | BTKPPARDPPARA | |
| SCHEMBL29637933 | 0.90 | CNR1 (0.44) | BTKPPARDPPARA | |
| SCHEMBL29637984 | 0.90 | KMT2A (0.44) | BTKJAK3PPARDPPARA | |
| SCHEMBL29017647 | 0.89 | BTK (0.52) | BTKJAK3LCKEGFR | |
| SCHEMBL29017745 | 0.89 | BTK (0.56) | BTKJAK3LCKPPARDPPARA | |
| SCHEMBL29637931 | 0.88 | BTK (0.53) | BTKJAK3LCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478478-B | N- (1- (6- (substituted phenyl) pyridazin-3-yl) piperidin-3-yl) amine/amide derivatives and process for preparing the same | 厦门大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114478478-A | N- (1- (6- (substituted phenyl) pyridazine-3-yl) piperidine-3-yl) amine/amide derivative and preparation method thereof | 厦门大学 | 2022-05-13 | — | — | CN | disclosed |