Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017740 | 1.00 | PPARA (0.44) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29017657 | 0.93 | KMT2A (0.43) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29637905 | 0.93 | KMT2A (0.43) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29017653 | 0.91 | CNR1 (0.44) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29637933 | 0.91 | CNR1 (0.44) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29017668 | 0.90 | PPARD (0.47) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29637924 | 0.90 | PPARD (0.47) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29017684 | 0.88 | KMT2A (0.43) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29637930 | 0.88 | KMT2A (0.43) | PPARAPPARDKMT2AMEN1BTK | |
| SCHEMBL29017698 | 0.88 | KMT2A (0.44) | PPARAPPARDKMT2AMEN1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478478-B | N- (1- (6- (substituted phenyl) pyridazin-3-yl) piperidin-3-yl) amine/amide derivatives and process for preparing the same | 厦门大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114478478-A | N- (1- (6- (substituted phenyl) pyridazine-3-yl) piperidine-3-yl) amine/amide derivative and preparation method thereof | 厦门大学 | 2022-05-13 | — | — | CN | disclosed |