SCHEMBL29638048

SCHEMBL29638048

CCC(C)(C)C(=O)N(O)Cc1ccc(F)c(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RIPK1 Q13546 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17882205 1.00 RIPK1 (1.00) RIPK1
SCHEMBL23803533 0.87 RIPK1 (0.78) RIPK1
SCHEMBL17882383 0.85 RIPK1 (0.74) RIPK1
SCHEMBL17874145 0.85 RIPK1 (1.00) RIPK1
SCHEMBL17874165 0.83 RIPK1 (1.00) RIPK1
SCHEMBL17882167 0.82 RIPK1 (0.70) RIPK1
SCHEMBL29912597 0.82 RIPK1 (0.72) RIPK1
SCHEMBL17874102 0.82 RIPK1 (0.72) RIPK1
SCHEMBL19448786 0.82 RIPK1 (0.69) RIPK1
SCHEMBL23803561 0.81 RIPK1 (0.75) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3612223-B1 TREATING MALE SENESCENCE NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) 2024-07-31 — — EP claimed
CN-117320754-A Prostatitis treatment 北京生命科学研究所 2023-12-29 — — CN disclosed
CN-115197098-B Cell necrosis inhibitor 北京生命科学研究所 2023-08-08 — — CN disclosed
CN-115197098-A Cell necrosis inhibitor 北京生命科学研究所 2022-10-18 — — CN disclosed
CN-107108467-B Cell necrosis inhibitor 北京生命科学研究所 2022-08-19 — — CN disclosed
EP-4017535-A1 PROSTATITIS TREATMENT National Institute Of Biological Sciences, Beijing (CN) 2022-06-29 — — EP disclosed
CN-110769853-B Treatment of male aging 北京生命科学研究所 2022-06-03 — — CN disclosed
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