Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638382 | 0.85 | ABL1 (0.53) | KDM4EABL1NPC1RAB9AGSK3B | |
| SCHEMBL29638418 | 0.82 | ABL1 (0.44) | ALKBH5KDM4EABL1NPC1RAB9A | |
| SCHEMBL24557271 | 0.79 | SRC (0.46) | ALKBH5PLK1PIK3CAPRKDCGABRA1 | |
| SCHEMBL29638496 | 0.79 | SRC (0.46) | ALKBH5PLK1PIK3CAPRKDCGABRA1 | |
| SCHEMBL24557279 | 0.79 | MEN1 (0.42) | ALKBH5HPGDPLK1PIK3CAPRKDC | |
| SCHEMBL29638478 | 0.79 | MEN1 (0.42) | ALKBH5HPGDPLK1PIK3CAPRKDC | |
| SCHEMBL24557282 | 0.77 | POLB (0.42) | ALKBH5HPGDPLK1PIK3CAPRKDC | |
| SCHEMBL29638556 | 0.77 | POLB (0.42) | ALKBH5HPGDPLK1PIK3CAPRKDC | |
| SCHEMBL29638400 | 0.77 | LYN (0.42) | ALKBH5KDM4EHPGDPLK1PIK3CA | |
| SCHEMBL24557272 | 0.76 | BTK (0.45) | PLK1PIK3CAPRKDCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |