Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 9/20 | 0.47 |
| ▸ | RAF1 | P04049 | 4/20 | 0.47 |
| ▸ | LCK | P06239 | 4/20 | 0.34 |
| ▸ | TEK | Q02763 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291272 | 0.78 | BRAF (0.57) | BRAFRAF1LCKTEKKDR | |
| SCHEMBL30559484 | 0.78 | BRAF (0.57) | BRAFRAF1LCKTEKKDR | |
| SCHEMBL29638508 | 0.74 | BRAF (0.35) | BRAFRAF1LCKTEKKDR | |
| SCHEMBL15067099 | 0.72 | BRAF (0.51) | BRAFRAF1LCKTEKKDR | |
| SCHEMBL30402025 | 0.72 | BRAF (0.51) | BRAFRAF1LCKTEKKDR | |
| SCHEMBL29638623 | 0.68 | KDM1A (0.38) | BRAFRAF1LCKTEKKDR | |
| SCHEMBL29638749 | 0.67 | BRAF (0.38) | BRAFLCKTEKKDR | |
| SCHEMBL24399608 | 0.66 | BRAF (0.78) | BRAFRAF1LCKTEKKDR | |
| SCHEMBL30402406 | 0.66 | BRAF (0.78) | BRAFRAF1LCKTEKKDR | |
| SCHEMBL30559436 | 0.65 | BRAF (0.43) | BRAFRAF1LCKTEKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |