Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 9/20 | 0.46 |
| ▸ | BRAF | P15056 | 9/20 | 0.46 |
| ▸ | AURKA | O14965 | 7/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.43 |
| ▸ | CSF1R | P07333 | 5/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.41 |
| ▸ | ARAF | P10398 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.39 |
| ▸ | SCD | O00767 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374156 | 1.00 | RAF1 (0.46) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL25376849 | 0.93 | RAF1 (0.48) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL30402514 | 0.91 | RAF1 (0.50) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL24399704 | 0.91 | RAF1 (0.50) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL30402843 | 0.90 | RAF1 (0.54) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL24399573 | 0.90 | RAF1 (0.54) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL29638589 | 0.89 | RAF1 (0.47) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL24399589 | 0.89 | RAF1 (0.47) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL25375338 | 0.89 | RAF1 (0.49) | RAF1BRAFAURKARPS6KB1CSF1R | |
| SCHEMBL30401795 | 0.89 | RAF1 (0.49) | RAF1BRAFAURKARPS6KB1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |