Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30398394 | 0.84 | ABCG2 (0.64) | EGFRABCG2AURKATSHRHTT | |
| SCHEMBL806052 | 0.84 | ABCG2 (0.64) | EGFRABCG2AURKATSHRHTT | |
| SCHEMBL13686770 | 0.81 | MAPK1 (0.56) | EGFRABCG2HTTPOLBMEN1 | |
| SCHEMBL29638626 | 0.78 | BRAF (0.58) | EGFRABCG2TSHRHTTLMNA | |
| SCHEMBL2261398 | 0.78 | BRAF (0.58) | EGFRABCG2AURKATSHRHTT | |
| SCHEMBL2265817 | 0.78 | BRAF (0.58) | EGFRABCG2TSHRHTTLMNA | |
| SCHEMBL30754777 | 0.78 | LMNA (0.65) | EGFRABCG2AURKATSHRHTT | |
| SCHEMBL8373657 | 0.78 | EGFR (0.76) | EGFRABCG2TSHRHTTLMNA | |
| SCHEMBL10215930 | 0.76 | LMNA (0.64) | EGFRABCG2AURKATSHRHTT | |
| SCHEMBL10835262 | 0.75 | LMNA (0.56) | EGFRABCG2AURKATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |