SCHEMBL29638797

SCHEMBL29638797

CCCN(CCc1ccc(OC)cc1)C(=O)C1=Cc2ccccc2N=CC1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 15/20 0.47
LPAR1 Q92633 1/20 0.41
LPAR5 Q9H1C0 1/20 0.41
ALOX5 P09917 2/20 0.40
TLR7 Q9NYK1 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17843467 0.86 TP53 (0.49) TLR8TLR7
SCHEMBL29638773 0.86 TP53 (0.49) TLR8TLR7
SCHEMBL30831287 0.82 TLR8 (0.45) TLR8TLR7
SCHEMBL29638794 0.79 TLR8 (0.49) TLR8TLR7
SCHEMBL29638792 0.78 TLR8 (0.43) TLR8TLR7
SCHEMBL30007216 0.76 TLR8 (0.38) TLR8TLR7
SCHEMBL30541811 0.75 TLR8 (0.35) TLR8TLR7
SCHEMBL29638774 0.74 TLR8 (0.43) TLR8TLR7
SCHEMBL29638788 0.70 TLR8 (0.43) TLR8TLR7
SCHEMBL30831270 0.70 TP53 (0.42) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114585390-A Aminobenzazepine compounds, immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2022-06-03 CN disclosed