Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 18/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30831287 | 0.94 | TLR8 (0.45) | TLR8TLR7TP53 | |
| SCHEMBL29638773 | 0.88 | TP53 (0.49) | TLR8TLR7TP53 | |
| SCHEMBL17843467 | 0.88 | TP53 (0.49) | TLR8TLR7TP53 | |
| SCHEMBL29638792 | 0.81 | TLR8 (0.43) | TLR8TLR7TP53 | |
| SCHEMBL29638794 | 0.80 | TLR8 (0.49) | TLR8TLR7TP53 | |
| SCHEMBL29638774 | 0.78 | TLR8 (0.43) | TLR8TLR7 | |
| SCHEMBL28815824 | 0.77 | P2RX4 (0.37) | — | |
| SCHEMBL8802496 | 0.76 | TRPA1 (0.37) | — | |
| SCHEMBL30831316 | 0.76 | TP53 (0.39) | TLR8TLR7TP53 | |
| SCHEMBL30541811 | 0.75 | TLR8 (0.35) | TLR8TLR7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801107-A | Benzazepine derivatives, conjugates containing same and application thereof | 上海迪诺医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115448917-A | Nitrogen-containing compound, conjugate containing nitrogen-containing compound and application of conjugate | 上海迪诺医药科技有限公司 | 2022-12-09 | — | — | CN | disclosed |