Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960913 | 0.98 | NR1H2 (0.39) | GPR84HSD11B1NR1H2NR1H3PTPN1 | |
| SCHEMBL2964405 | 0.98 | NR1H2 (0.39) | GPR84HSD11B1NR1H2NR1H3PTPN1 | |
| SCHEMBL2972875 | 0.98 | NR1H2 (0.39) | GPR84HSD11B1NR1H2NR1H3PTPN1 | |
| SCHEMBL2964258 | 0.98 | NR1H2 (0.39) | GPR84HSD11B1NR1H2NR1H3PTPN1 | |
| SCHEMBL2964832 | 0.98 | NR1H2 (0.39) | GPR84HSD11B1NR1H2NR1H3PTPN1 | |
| SCHEMBL2973993 | 0.95 | HSD11B1 (0.36) | GPR84HSD11B1NR1H2NR1H3PTPN1 | |
| SCHEMBL2963710 | 0.91 | HSD11B1 (0.36) | HSD11B1NR1H2NR1H3PTPN1CNR1 | |
| SCHEMBL2974780 | 0.89 | NR1H2 (0.38) | HSD11B1NR1H2NR1H3PTPN1CNR1 | |
| SCHEMBL2965085 | 0.89 | NR1H2 (0.38) | HSD11B1NR1H2NR1H3PTPN1CNR1 | |
| SCHEMBL2970997 | 0.89 | NR1H2 (0.38) | HSD11B1NR1H2NR1H3PTPN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | GPR84 3428/4885HSD11B1 4377/4885NR1H2 1227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.