Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403643 | 0.82 | GAA (0.72) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9618201 | 0.82 | CA12 (0.50) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2330668 | 0.81 | PLAU (0.61) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7623605 | 0.81 | GAA (0.70) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6416051 | 0.80 | PLAU (0.56) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL28694398 | 0.80 | CA12 (0.48) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL30151494 | 0.79 | PTPN11 (0.58) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10479344 | 0.79 | CA12 (0.61) | GAAMAPTABL1SLC6A2SLC6A4 | |
| SCHEMBL17922667 | 0.79 | CYP2A6 (0.50) | ALDH1A1KDM4EHPGDMAPTTDP1 | |
| SCHEMBL26882759 | 0.79 | KDM4E (0.57) | GAAALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845458-B | Fluorescent probe for detecting pyroglutamyl aminopeptidase I and preparation method and application thereof | 西北工业大学 | 2022-05-17 | — | — | CN | disclosed |