Sugi Predict

Sugi Predict / Compounds / SCHEMBL1403643

SCHEMBL1403643

SCHEMBL1403643

COC(=O)c1ccc(N)cc1C(=O)OC

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 6/20 0.72
▸ ALDH1A1 P00352 7/20 0.56
▸ KDM4E B2RXH2 7/20 0.56
▸ MAPT P10636 6/20 0.56
▸ HSD17B10 Q99714 4/20 0.56
▸ HPGD P15428 3/20 0.56
▸ GLA P06280 2/20 0.56
▸ CASP1 P29466 2/20 0.56
▸ CASP7 P55210 2/20 0.56
▸ ATM Q13315 1/20 0.56
▸ ABL1 P00519 1/20 0.55
▸ CFTR P13569 2/20 0.52
▸ CA12 O43570 2/20 0.50
▸ CA1 P00915 2/20 0.50
▸ CA2 P00918 2/20 0.50
▸ CA7 P43166 2/20 0.50
▸ CA9 Q16790 2/20 0.50
▸ CA14 Q9ULX7 2/20 0.50
▸ PDK2 Q15119 1/20 0.50
▸ PDK4 Q16654 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7623605 0.98 GAA (0.70) GAAALDH1A1KDM4EMAPTHSD17B10
Dimethyl Phthalate SCHEMBL28028655 0.94 GAA (0.66) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL29922154 0.90 GAA (0.66) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL9648251 0.90 GAA (0.66) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL9398149 0.90 GAA (0.66) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL28627930 0.88 GAA (0.58) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL10289753 0.87 GAA (0.62) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL6168887 0.86 GAA (0.66) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL29400478 0.86 GAA (0.70) GAAALDH1A1KDM4EMAPTHSD17B10
SCHEMBL2926607 0.86 GAA (0.70) GAAALDH1A1KDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110981715-B Protein chemical cross-linking agent and preparation method and application thereof 北京大学 2021-08-10 — — CN claimed
CN-110981715-A Protein chemical cross-linking agent and preparation method and application thereof 北京大学 2020-04-10 — — CN claimed
CN-104530221-B A kind of synthetic method of phthalate compound general artificial antigen 西南大学 2017-09-01 — — CN claimed
CN-105085765-B A kind of preparation method of repefral molecular engram microsphere 浙江农林大学 2017-03-08 — — CN claimed
CN-105085765-A Preparation method for dimethyl phthalate molecularly imprinted microspheres UNIV ZHEJIANG A&F 2015-11-25 — — CN claimed
CN-104530221-A Synthetic method of phthalic acid ester compound general artificial antigen UNIV SOUTHWEST 2015-04-22 — — CN claimed
CN-102692503-B Colloidal gold test paper card for detecting dimethyl phthalate and preparation method of colloidal gold test paper card UNIV HENAN SCIENCE & TECH 2014-07-30 — — CN claimed
CN-102692503-A Colloidal gold test paper card for detecting dimethyl phthalate and preparation method of colloidal gold test paper card UNIV HENAN SCIENCE & TECH 2012-09-26 — — CN claimed
JP-58069255-A — — None — — JP disclosed
EP-4695235-A1 NOVEL GSPT1 DEGRADER AND USE THEREOF Cyrus Therapeutics Inc. (KR) 2026-02-18 — — EP disclosed
EP-4622967-A1 COMPOUNDS THAT INHIBIT PKMYT1 Exelixis, Inc. (US) 2025-10-01 — — EP disclosed
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 ZHOU YUHANG (US) 2025-09-11 — — US disclosed
CN-119684303-A Heterocyclic compound of difunctional degradable androgen receptor and application thereof 上海超阳药业有限公司 2025-03-25 — — CN disclosed
US-20250011330-A1 Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors LEIDOS BIOMEDICAL RESEARCH INC. 2025-01-09 — — US disclosed
EP-0280156-A2 Process for the preparation of acetoacetylarylamides-heteroarylamides respectively of deactived aromatic compounds HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-31 — — EP disclosed
EP-0065811-B1 DISPERSE AZOPYRIMIDINE DYESTUFFS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-02 — — EP disclosed
JP-S5869255-A PHTHALOCYANINE DERIVATIVE MATSUSHITA ELECTRIC IND CO LTD 1983-04-25 — — JP disclosed
US-4145522-A Polyimide from amino substituted 4-t-butylphthalic anhydride STANDARD OIL COMPANY (INDIANA) (US) 1979-03-20 — — US disclosed
US-4078142-A Amino substituted-4-t-butylphthalic acid esters STANDARD OIL COMPANY (US) 1978-03-07 — — US disclosed
JP-S05869255-A — — 0001-01-01 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 PF4, F12, F2 GAA 4440/4885ALDH1A1 4728/4885KDM4E 1473/4885
US-20250011330-A1 Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors TDP1, TDP2, TOP1 GAA 2339/4885ALDH1A1 769/4885KDM4E 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.