Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28756085 | 1.00 | ALDH1A1 (0.43) | ALDH1A1GAAKDM4EATMGLA | |
| SCHEMBL28756094 | 0.85 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4EATMGLA | |
| SCHEMBL16106322 | 0.84 | ALDH1A1 (0.56) | ALDH1A1GAAKDM4EATMGLA | |
| SCHEMBL1847413 | 0.83 | MAPK14 (0.39) | ALDH1A1HTTSMN1; SMN2KMT2AMAPK14 | |
| SCHEMBL28756187 | 0.81 | MAPK14 (0.50) | ALDH1A1GAAKDM4EATMGLA | |
| SCHEMBL28756204 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EATMGLA | |
| SCHEMBL29639431 | 0.81 | MAPK14 (0.50) | ALDH1A1GAAKDM4EATMGLA | |
| SCHEMBL29639427 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EATMGLA | |
| SCHEMBL16106410 | 0.80 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL29639413 | 0.80 | GSK3A (0.51) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440073-B1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LTD (GB) | 2022-06-08 | — | — | EP | disclosed |