Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530627 | 0.88 | EPHX2 (0.47) | EPHX1EPHX2KMT2ACHRM3OPRD1 | |
| SCHEMBL29639579 | 0.86 | EPHX2 (0.41) | EPHX1EPHX2KMT2ACHRM3OPRD1 | |
| SCHEMBL29639589 | 0.86 | EPHX2 (0.42) | EPHX1EPHX2KMT2AKCNA5MDM4 | |
| SCHEMBL21677939 | 0.86 | EPHX2 (0.42) | EPHX1EPHX2KMT2AKCNA5MDM4 | |
| SCHEMBL20530629 | 0.85 | CHRM3 (0.45) | EPHX1EPHX2KMT2ACHRM3 | |
| SCHEMBL20530645 | 0.81 | CHRM3 (0.44) | EPHX1EPHX2KMT2ACHRM3 | |
| SCHEMBL18688054 | 0.81 | EPHX2 (0.53) | EPHX1EPHX2KMT2ACHRM3OPRD1 | |
| SCHEMBL29639572 | 0.81 | EPHX2 (0.43) | EPHX1EPHX2KMT2ACHRM3OPRD1 | |
| SCHEMBL20530673 | 0.79 | KMT2A (0.42) | EPHX2KMT2ACHRM3OPRD1 | |
| SCHEMBL20530641 | 0.79 | PTGDR2 (0.45) | EPHX2KMT2ACHRM3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609905-B1 | PEPTIDE MACROCYCLES AND USE THEREOF IN THE TREATMENT OF BACTERIAL INFECTIONS | HOFFMANN LA ROCHE (CH) | 2022-06-08 | — | — | EP | disclosed |