Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466820 | 0.86 | EPHX2 (0.40) | EPHX2KMT2AP2RX7KDM4ELMNA | |
| SCHEMBL20530632 | 0.86 | EPHX2 (0.40) | EPHX2KMT2AP2RX7KDM4ELMNA | |
| SCHEMBL29639583 | 0.86 | EPHX1 (0.43) | EPHX2KMT2AEPHX1CHRM3OPRD1 | |
| SCHEMBL20530666 | 0.86 | RBP4 (0.41) | EPHX2KMT2AP2RX7NR1H2NR1H3 | |
| SCHEMBL20530627 | 0.85 | EPHX2 (0.47) | EPHX2KMT2AEPHX1CHRM3OPRD1 | |
| SCHEMBL20530673 | 0.84 | KMT2A (0.42) | EPHX2KMT2ACHRM3OPRD1MEN1 | |
| SCHEMBL20530641 | 0.84 | PTGDR2 (0.45) | EPHX2KMT2ACHRM3OPRD1MEN1 | |
| SCHEMBL20530650 | 0.80 | KMT2A (0.47) | EPHX2KMT2AP2RX7OPRD1KDM4E | |
| SCHEMBL18688054 | 0.79 | EPHX2 (0.53) | EPHX2KMT2AEPHX1CHRM3OPRD1 | |
| SCHEMBL20530629 | 0.79 | CHRM3 (0.45) | EPHX2KMT2AEPHX1CHRM3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609905-B1 | PEPTIDE MACROCYCLES AND USE THEREOF IN THE TREATMENT OF BACTERIAL INFECTIONS | HOFFMANN LA ROCHE (CH) | 2022-06-08 | — | — | EP | disclosed |