SCHEMBL29639595

SCHEMBL29639595

COc1c(C(=O)/C=C(\O)c2ccccc2)ccc2oc(-c3ccc(OCc4ccccc4)c(C)c3)cc12

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 4/20 0.50
CYP1B1 Q16678 3/20 0.50
ABCB1 P08183 1/20 0.50
MRGPRX4 Q96LA9 6/20 0.44
CYP1A2 P05177 2/20 0.41
MCL1 Q07820 1/20 0.39
FFAR4 Q5NUL3 1/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
PTGER1 P34995 1/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28738868 1.00 CYP1A1 (0.50) CYP1A1CYP1B1ABCB1MRGPRX4CYP1A2
SCHEMBL29639597 0.91 CYP1A1 (0.49) CYP1A1CYP1B1ABCB1MRGPRX4CYP1A2
SCHEMBL28738872 0.91 CYP1A1 (0.49) CYP1A1CYP1B1ABCB1MRGPRX4CYP1A2
SCHEMBL29639590 0.91 CYP1A1 (0.49) CYP1A1CYP1B1ABCB1MRGPRX4CYP1A2
SCHEMBL30406675 0.88 CYP1A1 (0.53) CYP1A1CYP1B1ABCB1MRGPRX4CYP1A2
SCHEMBL28738858 0.88 CYP1A1 (0.53) CYP1A1CYP1B1ABCB1MRGPRX4CYP1A2
SCHEMBL29639588 0.88 CYP1A1 (0.53) CYP1A1CYP1B1ABCB1MRGPRX4CYP1A2
SCHEMBL29639591 0.88 CYP1A1 (0.53) CYP1A1CYP1B1ABCB1MRGPRX4CYP1A2
SCHEMBL28738854 0.87 L3MBTL1 (0.46) CYP1A1CYP1B1MRGPRX4CYP1A2MCL1
SCHEMBL29639592 0.87 L3MBTL1 (0.46) CYP1A1CYP1B1MRGPRX4CYP1A2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507201-B Water wampee seed element derivative and preparation method and application thereof 常州大学 2023-06-27 CN disclosed
CN-114507201-A Cortinarius fruit seed derivative and preparation method and application thereof 常州大学 2022-05-17 CN disclosed