SCHEMBL29639664

SCHEMBL29639664

CSc1cc(C(=O)O)cc(C(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.37
TPMT P51580 3/20 0.36
MCL1 Q07820 1/20 0.36
AKR1C3 P42330 4/20 0.36
AKR1C2 P52895 4/20 0.36
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA7 P43166 3/20 0.33
CA9 Q16790 3/20 0.33
CA14 Q9ULX7 3/20 0.33
PHGDH O43175 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
HCAR1 Q9BXC0 2/20 0.32
CA3 P07451 2/20 0.32
CA4 P22748 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22926161 1.00 DAO (0.37) DAOTPMTMCL1AKR1C3AKR1C2
SCHEMBL29639656 0.84 CYP3A4 (0.34) AKR1C3AKR1C2HPGDSMN1; SMN2ALOX15
SCHEMBL28944972 0.84 CYP3A4 (0.34) AKR1C3AKR1C2HPGDSMN1; SMN2ALOX15
SCHEMBL11678326 0.84 FABP3 (0.44) TPMTMCL1AKR1C3AKR1C2HPGD
SCHEMBL14240279 0.80 TPMT (0.48) TPMTMCL1HPGDHSD17B10CYP1A2
SCHEMBL28097872 0.80 DAO (0.47) DAOTPMTHPGDHSD17B10CYP1A2
SCHEMBL11677798 0.80 TPMT (0.48) TPMTMCL1HPGDHSD17B10CYP1A2
SCHEMBL879318 0.76 HCAR1 (0.53) TPMTMCL1HPGDHSD17B10CYP1A2
SCHEMBL29639647 0.75 MRGPRX4 (0.40) TPMTMCL1AKR1C3AKR1C2MRGPRX4
SCHEMBL22926043 0.75 MRGPRX4 (0.40) TPMTMCL1AKR1C3AKR1C2MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561817-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2024-08-30 CN disclosed
CN-118496198-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2024-08-16 CN disclosed
CN-114761402-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2022-07-15 CN disclosed
CN-114502545-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2022-05-13 CN disclosed