SCHEMBL29639667

SCHEMBL29639667

O=C(O)c1cc(C2CC2)cc(S(=O)(=O)C2CC2)c1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.43
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
KMO O15229 1/20 0.41
CYP1A2 P05177 1/20 0.38
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
CREBBP Q92793 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
TPMT P51580 1/20 0.33
DRD2 P14416 1/20 0.33
CNR1 P21554 1/20 0.33
MAPT P10636 1/20 0.32
IL1RN P18510 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22926375 1.00 AKR1C3 (0.43) AKR1C3LCKFYNKMOCYP1A2
SCHEMBL29639680 0.82 LCK (0.43) AKR1C3LCKFYNKMOCYP1A2
SCHEMBL12097672 0.82 LCK (0.43) AKR1C3LCKFYNKMOCYP1A2
SCHEMBL4392929 0.80 KMO (0.55) KMOALDH1A1CREBBPMRGPRX4TPMT
SCHEMBL23375706 0.79 TPMT (0.57) AKR1C3LCKFYNCYP1A2TPMT
SCHEMBL184302 0.78 KMO (0.53) LCKFYNKMOALDH1A1CREBBP
SCHEMBL29728799 0.78 LCK (0.40) AKR1C3LCKFYNKMOCYP1A2
SCHEMBL23412071 0.78 LCK (0.40) AKR1C3LCKFYNKMOCYP1A2
SCHEMBL23464782 0.76 AKR1C3 (0.42) AKR1C3LCKFYNCYP1A2MEN1
SCHEMBL21225183 0.73 AKR1C3 (0.71) AKR1C3KMOMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003974-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-06-01 EP claimed
CN-118561817-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2024-08-30 CN disclosed
CN-118496198-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2024-08-16 CN disclosed
CN-114502545-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2022-05-13 CN disclosed