SCHEMBL29639739

SCHEMBL29639739

CC(=O)c1cccc(C)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.65
HDAC8 Q9BY41 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
KCNK3 O14649 2/20 0.60
KCNK9 Q9NPC2 2/20 0.60
KCNH2 Q12809 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.58
HPGD P15428 2/20 0.58
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
ALDH1A1 P00352 2/20 0.58
LMNA P02545 1/20 0.58
ALOX12 P18054 1/20 0.58
STAT1 P42224 1/20 0.58
MAOB P27338 1/20 0.57
CYP2A6 P11509 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
RXFP1 Q9HBX9 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76212 1.00 PARP1 (0.65) PARP1HDAC8HDAC6KCNK3KCNK9
Fluoride SCHEMBL27643407 0.98 PARP1 (0.63) PARP1HDAC8HDAC6KCNK3KCNK9
SCHEMBL8264151 0.87 DHODH (0.54) PARP1KCNK3KCNK9KCNH2SMN1; SMN2
Benzenethiol SCHEMBL27858661 0.87 SMN1; SMN2 (0.54) PARP1HDAC8HDAC6KCNK3KCNK9
Pyrimidine SCHEMBL27517631 0.87 PARP1 (0.52) PARP1HDAC8HDAC6KCNK3KCNK9
SCHEMBL24689975 0.86 CYP2A6 (0.62) PARP1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL279656 0.85 ALDH1A1 (0.59) SMN1; SMN2NPC1RAB9AALDH1A1MAOB
SCHEMBL21377679 0.84 KCNK3 (0.84) KCNK3KCNK9KCNH2SMN1; SMN2HPGD
SCHEMBL186545 0.83 PARP1 (0.68) PARP1HDAC8HDAC6KCNK3KCNK9
SCHEMBL3753879 0.83 PARP1 (0.68) PARP1HDAC8HDAC6KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114502659-A Resin composition, resin sheet, cured film, method for producing cured film, semiconductor device, organic EL display device, and display device 东丽株式会社 2022-05-13 CN disclosed