SCHEMBL29639779

SCHEMBL29639779

CC(C)(O)Cn1c(CCOCC(F)(F)F)nc2c(N)nc3ccccc3c21

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.68
TLR8 Q9NR97 12/20 0.68
NUDT1 P36639 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24808210 1.00 TLR7 (0.68) TLR7TLR8NUDT1
SCHEMBL23637762 0.90 TLR7 (0.79) TLR7TLR8NUDT1
SCHEMBL3518277 0.87 TLR7 (0.75) TLR7TLR8NUDT1
SCHEMBL29639770 0.87 TLR7 (0.75) TLR7TLR8NUDT1
SCHEMBL24808853 0.87 TLR7 (0.75) TLR7TLR8NUDT1
SCHEMBL24808069 0.85 TLR7 (0.79) TLR7TLR8NUDT1
SCHEMBL29639792 0.84 TLR7 (0.71) TLR7TLR8NUDT1
SCHEMBL24808484 0.84 TLR7 (0.71) TLR7TLR8NUDT1
SCHEMBL24807103 0.84 TLR7 (0.76) TLR7TLR8NUDT1
SCHEMBL29639786 0.84 TLR7 (0.76) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599360-A 4-amino-imidazoquinoline compounds and uses thereof 骏达贸易有限公司 2022-06-07 CN claimed
US-20220411421-A1 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF CHOU, YU-CHENG (TW) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411421-A1 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF TLR7, TLR8, TLR6 TLR7 1/4885TLR8 2/4885NUDT1 789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.