SCHEMBL29640109

SCHEMBL29640109

COc1cc(C(C)=O)ccn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 1/20 0.55
KCNK9 Q9NPC2 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.50
PROKR1 Q8TCW9 2/20 0.46
LOX P28300 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CTSA P10619 1/20 0.43
CNR1 P21554 1/20 0.42
FFAR1 O14842 1/20 0.41
LMNA P02545 1/20 0.41
KDM6B O15054 1/20 0.41
KDM5C P41229 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41
KDM3A Q9Y4C1 1/20 0.41
NNMT P40261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12640026 1.00 KCNK3 (0.55) KCNK3KCNK9SMN1; SMN2PROKR1LOX
SCHEMBL27841468 0.86 KCNK3 (0.52) KCNK3KCNK9PROKR1LOXLOXL2
SCHEMBL229446 0.85 KDM4C (0.57) KCNK3KCNK9PROKR1LOXLOXL2
SCHEMBL29556902 0.85 KDM4C (0.57) KCNK3KCNK9PROKR1LOXLOXL2
Hydrochloric Acid SCHEMBL5564185 0.83 KDM4C (0.56) KCNK3KCNK9PROKR1LOXLOXL2
SCHEMBL30281222 0.83 NNMT (0.56) KCNK3KCNK9PROKR1LOXLOXL2
SCHEMBL16168468 0.83 KCNK3 (0.50) KCNK3KCNK9PROKR1LOXLOXL2
SCHEMBL31637653 0.83 KCNK3 (0.50) KCNK3KCNK9PROKR1LOXLOXL2
SCHEMBL29587235 0.83 KDM4E (0.61) KCNK3KCNK9SMN1; SMN2PROKR1LOX
SCHEMBL2431121 0.83 KCNK3 (0.50) KCNK3KCNK9PROKR1LOXLOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735423-A1 KV7 MODULATORS Saniona A/S (DK) 2026-05-06 EP disclosed
WO-2025003343-A1 KV7 MODULATORS SANIONA A/S (DK) 2025-01-02 WO disclosed
CN-114450271-B Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition 纽力克斯治疗公司 2024-09-20 CN disclosed
CN-115279741-A 4-phenyl-N- (phenyl) thiazol-2-amine derivatives and related compounds as Aryl Hydrocarbon Receptor (AHR) agonists for the treatment of, for example, angiogenesis-related disorders or inflammatory disorders 医肯纳肿瘤学公司 2022-11-01 CN disclosed
EP-3440078-B1 HETEROCYCLIC GPR119 AGONIST COMPOUNDS MANKIND PHARMA LTD (IN) 2022-09-28 EP disclosed
CN-114450271-A Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition 纽力克斯治疗公司 2022-05-06 CN disclosed