⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47225 | 0.75 | — | — | |
| SCHEMBL31118216 | 0.57 | — | — | |
| SCHEMBL18173809 | 0.51 | — | — | |
| Fluoride SCHEMBL31379722 | 0.51 | — | — | |
| SCHEMBL15568358 | 0.51 | MEN1 (0.33) | — | |
| SCHEMBL2182073 | 0.47 | — | — | |
| SCHEMBL1462204 | 0.45 | — | — | |
| SCHEMBL2213796 | 0.45 | — | — | |
| SCHEMBL31193696 | 0.43 | — | — | |
| SCHEMBL21111126 | 0.43 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026107377-A1 | PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL | KARANICOLAS JOHN (US) | 2026-05-21 | — | — | WO | disclosed |
| WO-2024231852-A1 | SUBSTITUTED BIPHENYL COMPOUNDS AS CBL-B INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2024-11-14 | — | — | WO | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |