Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29712074 | 0.97 | RXFP1 (0.53) | RXFP1MAOAMAOBPOLBSIGMAR1 | |
| SCHEMBL29640447 | 0.95 | RXFP1 (0.56) | RXFP1MAOAMAOBPOLBSIGMAR1 | |
| SCHEMBL29640490 | 0.93 | RXFP1 (0.56) | RXFP1POLBSIGMAR1KMT2A | |
| SCHEMBL29640470 | 0.92 | RXFP1 (0.53) | RXFP1MAOAMAOBPOLBSIGMAR1 | |
| SCHEMBL29640473 | 0.92 | RXFP1 (0.53) | RXFP1POLBSIGMAR1KMT2A | |
| SCHEMBL28741971 | 0.92 | SIGMAR1 (0.53) | SIGMAR1SMN1; SMN2DPP4 | |
| SCHEMBL29640457 | 0.92 | RXFP1 (0.56) | RXFP1MAOAMAOBPOLBSIGMAR1 | |
| SCHEMBL29640165 | 0.91 | POLB (0.57) | MAOAMAOBPOLBSIGMAR1KMT2A | |
| SCHEMBL29640464 | 0.90 | SIGMAR1 (0.50) | RXFP1MAOAMAOBPOLBSIGMAR1 | |
| SCHEMBL22966092 | 0.90 | POLB (0.50) | RXFP1MAOAMAOBPOLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450006-A | TrkB positive allosteric modulators | 斯特拉斯堡大学 | 2022-05-06 | — | — | CN | claimed |
| CN-114450006-A | TrkB positive allosteric modulators | 斯特拉斯堡大学 | 2022-05-06 | — | — | CN | disclosed |